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of using calcium chloride 10% solution for injection

as an anti-inflammatory, hemostatic and desensitizing agent for animals

(Organization-developer: “BioKhimPharm”, Vladimirskaya   region, Raduzhny town)

I. General information

1. Trade name of the medicinal product:  Calcii chloridi 10% solutio pro injectionibus.

International Nonproprietary Name: Calcium chloride.

2. Dosage form – injection solution.

The medicinal preparation in 100 ml as an active ingredient contains 10 g of calcium chloride, and as an auxiliary substance water for injection – up to 100 ml. In appearance, the preparation is a colorless transparent liquid.

3. Calcium chloride 10% solution for injection is issued in 10, 20, 50, 100, 200 ml prepackaged in glass bottles or 250, 400, 500 ml in glass bottles, sealed with rubber stoppers, reinforced with aluminum caps.

4. Store the preparation in the manufacturer’s closed container in a dry, protected from light place, at a temperature from 00C to 250C.

Shelf life of the drug under the storage conditions is 2 years from the date of manufacture. It is forbidden to use Calcium Chloride 10% solution for injection after the expiry date.

5. Calcium chloride 10% solution for injection should be stored out of the reach of children.

6. Dispose of unused product in accordance with legal requirements.

II. Pharmacological properties

7. Calcium chloride refers to the pharmacotherapeutic group of drugs that affect metabolism.

Calcium chloride 10% solution for injection in the body activates the reticuloendothelial system and phagocytic function of leukocytes, increases the tone of sympathetic innervation, increases the release of adrenaline, accelerates the production of many enzymes.

Calcium ions are needed to reduce skeletal muscle and heart muscle, bone formation, clotting of blood. Calcium ions condense the walls of blood vessels, thereby showing anti-inflammatory action and preventing the development of edema.

Calcium is involved in the process of blood clotting, promotes the conversion of prothrombin into thrombin.

After administration, the drug is rapidly absorbed from the injection site and distributed to the organs and tissues of the animal.

By the degree of exposure to the body Calcium chloride 10% solution for injection in accordance with GOST 12.1.007 refers to substances of low hazard (hazard class 4).

III. The order of application

8. Calcium chloride 10% solution for injection is used in animals to increase the calcium content in the blood, as an anti-inflammatory, hemostatic and desensitizing agent, to normalize the activity of the sympathetic nervous system in the following pathological conditions:

– pneumonia, pleurisy, peritonitis, toxic liver damage, parenchymal hepatitis, nephritis, radiation sickness, pulmonary edema, larynx, swelling of piglets;

– bleeding (uterine, gastrointestinal, pulmonary, postoperative) to reduce vascular permeability during hemorrhagic, inflammatory and exudative processes;

– Allergic diseases, allergic complications associated with the use of medicines;

– in obstetric-gynecological practice with endometritis, metritis, for stimulation of labor, acceleration of separation of delayed afterbirth in animals, prevention of abortion, in maternity paresis, postpartum haematuria in cows;

– with hypotension and atony of the prednagus, hemorrhagic gastroenteritis, tetany of young animals;

– with vegetative neuroses, eclampsia in dogs, acetonemia in cows, paralytic myoglobinuria in horses;

– when poisoning with magnesium salts, oxalic acid and its salts, sodium chloride.

9. Contraindication to the use of calcium chloride 10% solution for injection is an elevated calcium content in the blood and a tendency to thrombosis.

10. Calcium chloride 10% solution for injection is administered to the animals intravenously, slowly. If, with unsuccessful administration, a part of the solution has got subcutaneously, it is necessary to introduce a large amount of 0.9% isotonic sodium chloride solution around the site of injection to prevent tissue necrosis.

Maximum single doses (ml per animal):



150 – 400


100 -300

small cattle

10 – 30


10 – 20



Doses and timing of application depend on the weight of the animal and the course of the disease.

11. When an overdose of the drug in an animal, hypercalcemia may develop. To eliminate it, enter calcitonin dissolved in physiological solution in accordance with the instructions for use. In case of oppression of cardiac activity and the appearance of tachycardia, symptomatic treatment is used.

12. Features of the drug during its first use and cancellation is not established.

13. Failure to comply with the recommended interval with repeated administration of the drug may lead to a decrease in its effectiveness. If you skip the next dose of the drug, its use is resumed as soon as possible in the same dosage and according to the same scheme.

14. Calcium chloride 10% injection for injection only intravenously.

Intramuscular and subcutaneous administration of the drug is unacceptable, in view of the pronounced irritant effect of the drug, leading to tissue necrosis. In case of accidental ingestion of the drug under the skin to prevent tissue necrosis, a large amount of isotonic 0.9% isotonic solution should be injected around the injection site.

15. Information on the interaction of calcium chloride 10% solution for injection with other drugs and feed additives are not available.

16. Animal products derived from animals after the application of calcium chloride 10% solution for injection, can be used without restrictions.

IV. Personal prevention measures

17. When working with Calcium Chloride 10% solution for injection, you should observe the general rules of personal hygiene and safety, provided for working with medicines.

18. In case of accidental contact with the skin or mucous membranes of the eye, rinse immediately with plenty of water. People with hypersensitivity to the components of the drug should avoid direct contact with calcium chloride 10%. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (with you to have instructions for the use of the drug and a label).

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