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of using Amogen for the treatment of large and small cattle, horses, camels, pigs, dogs and cats in diseases of bacterial etiology

(Organization-developer: BioKhimPharm, 600910, Vladimir Region, Raduzhny, block 16, PO Box 74)

I. General information

1. Trade name of the medicinal product: Amogen. International non-proprietary name: amoxicillin trihydrate, gentamycin sulfate.

2. Dosage form: suspension for injection. Amogen contains as an active substance amoxicillin (in the form of amoxicillin trihydrate), gentamicin sulfate and auxiliary substances.

3. In appearance, the preparation is a sterile suspension of light yellow color. Shelf life of the drug under the conditions of storage – 2 years from the date of manufacture after opening the bottle – no more than 28 days. It is forbidden to use Amogen after its expiration date.

4. Release Amogen sterile packaged in 50, 100, 200 ml in glass bottles, hermetically sealed rubber stoppers, reinforced aluminum caps.

5. Store the medicinal product in the manufacturer’s closed packaging away from heating appliances, separate from food and feedstuffs, in a dry place protected from direct sunlight at a temperature of 50 ° C to 250 ° C.

6. Amogen should be stored in places inaccessible to children.

7. Dispose of unused product with expired shelf life in accordance with legal requirements.

8. Released without a veterinarian’s prescription.

II. Pharmacological properties

9. Amogen – a combined antibacterial drug.

10. The combination of amoxicillin and gentamycin has a broad antibacterial spectrum including gram-positive and gram-negative mycorrhizons (Actynomyces spp., Bacillus antracis, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Staphylococcus spp., Escherichia coli, Haemophilus spp., Pasteurella spp., Salmonella spp., Streptococcus spp, Actinobacillus spp., Proteus mirabilis, Leptospira spp.) Amoxicillin and gentamicin are well absorbed from the injection site and penetrate most of the organs and tissues of the animal’s body. The maximum concentration of amoxicillin is reached 1 hour after the injection and gentamicin after 30 minutes. Therapeutic concentrations persist for 24 hours. Antibiotics are excreted from the animal organism mainly with urine. By the degree of exposure to the body, Amogen refers to moderately hazardous substances (hazard class 3 according to GOST 12.1.007).

III. The order of application

11. Amogen is used for the treatment of large and small cattle, horses, camels, pigs, dogs and cats in infectious diseases of the gastrointestinal tract, respiratory tract, genitourinary system, joints, soft tissues and skin, necrobacteriosis, umbilical infections, atrophic rhinitis, syndrome of metritis-mastitis-agalactia and other primary and secondary infections of bacterial etiology.

12. Contraindications for the use of the drug is kidney disease, as well as increased individual sensitivity of animals to penicillins and aminoglycosides.

13. Amogen is administered intramuscularly once a day in a dose of 1 ml per 10 kg of animal weight for 3 days. Before each use, the vial with the preparation is shaken thoroughly until a uniform suspension is obtained. To administer the drug, use only dry syringes and needles. With large volumes of Amogen injection, it is recommended that the injection be carried out in several places to improve the absorption of the drug.

14. An overdose in animals at the injection site may lead to the development of edema, which resolves spontaneously within 1-2 days.

15. Features of the drug during the first admission or when it is canceled is not established.

16. The use of Amogen does not adversely affect the course of pregnancy, lactation and development of offspring in animals.

17. Passage of the next dose of the drug should be avoided, as this may lead to a decrease in therapeutic effectiveness. If the interval between two injections of the drug is accidentally increased, it should be administered as soon as possible.

18. When applying Amogen in accordance with this instruction, side effects and complications are usually not observed. In rare cases, the animal at the injection site may develop edema, which dissolves spontaneously within 1-2 days. With increased individual sensitivity of the animal to amoxicillin and the development of allergic reactions, the use of the drug is stopped and desensitizing therapy is administered.

19. Amogen should not be mixed in the same syringe with other drugs, nor can it be used concurrently with bacteriostatic chemotherapeutic drugs.

20. Slaughter animals for meat is allowed no earlier than 3 days after the last use of the drug. Meat of animals, who were forced to die before the expiration of this period, can be used in fodder for fur animals. Milk milking animals may be used for food purposes no earlier than 48 hours after the last administration of the drug. Milk, obtained during the treatment period and within 48 hours after the last administration of the drug, can be used after boiling in animal feed.

IV. Personal prevention measures

21. When working with a medicinal product, the general rules of personal hygiene and safety precautions prescribed in dealing with medicinal products should be observed.

22. When working with Amogen it is forbidden to drink, smoke and eat. Avoid contact with skin and mucous membranes. After working with the drug, wash your hands with soap and water. Empty vials from the drug are not allowed for household use.

23. In case of accidental contact with the skin or mucous membranes, rinse immediately with plenty of water. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (with you to have instructions for the use of the drug and a label).

Permanent link to this article: http://biohimfarm.ru/en/antibakter_r/amogen/