Instruction
on the use of the drug Trimast for the treatment of mastitis in farm animals
(Organization-developer: LLC Firm “Biochempharm”, Raduzhny, Vladimir region).
I. General information
1. Trade name of the drug: Trimast.
International nonproprietary name-oxytetracycline hydrochloride, furazolidone, prednisone.
2. Dosage form: suspension for topical use. Trimast as active substances in 1 ml contains in its composition oxytetracycline hydrochloride-50 mg, furazolidone-50 mg, prednisolone-1 mg and filler.
The preparation is an oil suspension of yellow color with a weak specific smell. At temperatures above 35°C, the suspension has a liquid consistency.
3. The drug is produced packaged in 10 cm3 in plastic syringes-dispensers or 50 cm3 and 100 cm3 in glass bottles of appropriate capacity, closed with rubber stoppers, reinforced aluminum caps. Other packing providing safety and quality of a preparation and coordinated in accordance with the established procedure is allowed.
Syringes-dispensers are Packed in 20 pieces in cardboard boxes along with instructions for use.
Shelf life of the drug-1.5 years from the date of production. Do not use the trimast After its expiration date.
4. The drug is stored in a dry, protected from direct sunlight at a temperature of 5°C to 25°C.
5. The trimmer should be kept out of the reach of children.
6. The drug is disposed of in accordance with applicable law.
II. Pharmacological properties
7. Pharmacotherapeutic group of the drug: combined antibacterial drugs.
Trimast has antibacterial effect, is effective against gram-positive and gram-negative microorganisms, prevents breast Allergy and promotes rapid removal of inflammatory response and regeneration of affected tissues.
Oxytetracycline hydrochloride destroys the vast majority of microorganisms that cause various forms of mastitis in animals.
Furazolidone is effective against microorganisms resistant to antibiotics and sulfonamides.
Prednisolone reduces the allergic effect of the antibiotic and furazolidone on the breast parenchyma and suppresses the inflammatory process.
The drug by the degree of exposure to the body refers to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76).
III. The order of application
8. Trimast is used to treat cows, mares, camels, ewes and goats with clinical and subclinical forms of bacterial etiology mastitis caused by microorganisms sensitive to the components of the drug during lactation.
9. Contraindicated in animals with increased individual sensitivity to the components of the drug.
10. Before the introduction of the drug from the patient quarter of the udder is milked secret, and the nipple is disinfected with 70% ethanol.
The drug before use is heated to 35-390C, recruited from the bottle with a sterile syringe and with the help of a catheter injected into the nipple of the affected udder lobe. When using a syringe, the cannula is pressed tightly against the opening of the nipple canal and the drug is administered.
The drug is administered intracysternally in the following doses (on the affected portion of the udder):
– in acute forms of mastitis-5 cm3;
– with prolonged (chronic) pathologies-10 cm3.
After the introduction of spend easy massage nipple from below-upward.
In the absence of a noticeable improvement after a single administration, the treatment is repeated 24 hours before recovery. For preventive purposes, the treatment of dead cows is carried out three weeks before birth.
11. Symptoms of overdose when using the drug in accordance with this instruction is not established.
12. In case manifestations of have animal signs of individual heightened sensitivity to drug in the early treatment, his the use of should abolish and to appoint means symptomatic therapy.
13. Failure to comply with the recommended interval for repeated administration of trimast can lead to a decrease in the effectiveness of Its use. At the admission of the next dose its application resume as soon as possible.
14. Side effects and complications with proper use and dosage of the drug is not observed. Animals sensitive to Trimast components may have allergic reactions.
15. The use of Trimast does not exclude the use of other drugs specific, pathogenetic and symptomatic therapy.
16. The use of milk obtained from healthy udder lobes in human food is permissible not earlier than 3 days after the last administration of the drug. Milk from patients with lobes-only after complete clinical recovery, confirmed by mastitis tests, but not earlier than the above period. Meat of slaughter animals is used in food to people without restrictions.
IV. Personal prevention measures
17. When working with the Trimmer, the General rules of personal hygiene and safety, provided for when working with medicines, should be observed. People with hypersensitivity to Trimast components should avoid direct contact with the drug.
18. When working with the drug, it is forbidden to drink, smoke and eat. After working with the Trimmer, wash your hands with soap and water.
19. In case of contact with the skin and mucous membranes should be washed with plenty of tap water. In case of accidental ingestion – give the victim to drink a large amount of water (4-5 glasses) and cause vomiting. In case of allergic reactions, you should immediately contact a medical institution (you should have the instructions for use of the drug and the label).
