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of using “Caffeine-sodium benzoate 20%” in veterinary medicine

(Organization-developer:  “BioKhimPharm”, Raduzhny, Vladimir region).

I. General information

1. Trade name of the medicinal product: Caffeine-sodium benzoate 20% (Coffeinum-natrii benzoas 20%).

International nonproprietary name: caffeine.

2. Dosage form: solution for injection. The preparation is a colorless transparent liquid. In 100 ml as an active substance contains sodium caffeine-benzoate 20 g and as auxiliary substances sodium hydroxide and water for injection.

Caffeine-sodium benzoate 20% packaged in 50 ml and 100 ml in glass bottles, hermetically sealed with rubber stoppers reinforced aluminum caps.

3. Each package is marked with the indication: the name of the manufacturing organization, its address and trademark, the name of the medicinal product; name and content of the active substance; the sign of conformity; quantities in the vial; number of the series (includes the date of manufacture); shelf life; inscriptions “Sterile” and “For veterinary use”; method of application; storage conditions; designations of the present Specification, put a bar code and provide instructions for use.

Shelf life Caffeine-sodium benzoate 20% solution for injection, subject to storage conditions – 2 years from the date of manufacture. Do not use the product after the expiration date.

4. Caffeine-sodium benzoate 20% should be stored in a dry, dark place at a temperature of 0 ° C to 25 ° C. Freezing is not allowed.

5. Caffeine-sodium benzoate 20% should be stored in places inaccessible to children.

6. Unused product with expired shelf life is disposed of in accordance with legal requirements.

II. Pharmacological properties

7. Pharmacotherapeutic group: a means that stimulates the central nervous system.

Caffeine-sodium benzoate 20% for injection has an exciting effect on the central nervous system of animals. It strengthens and regulates the processes of excitation in the cerebral cortex, enhances the positive conditioned reflexes and increases the motor activity. The stimulating effect of caffeine leads to an increase in physical performance, reducing fatigue and drowsiness. The effect of the drug depends on the dose, as well as on the type of higher nervous activity of animals. Large doses of the drug can lead to the depletion of nerve cells.

Under the influence of the drug, cardiac activity, diuresis, increased gas exchange, increased water and nitrogen metabolism.

Caffeine-sodium benzoate 20% for injection by the degree of exposure to the body according to GOST 12.1.007-76 refers to substances highly hazardous (2nd class of hazard).

III. The order of application

8. Sodium caffeine-benzoate 20% for injections is used to excite the central nervous system for poisoning with poisons, overfatigue, muscle weakness in various diseases.

Applied for the purpose of exciting the cardiovascular system with weakness of cardiac activity, reduced excitability and conduction in the heart, shock conditions. Applied with chronic myocarditis, myodystrophies, chronic myodegenations, as a vasodilator with spasms of the brain, kidneys, heart.

Caffeine-sodium benzoate 20% for injections is also used to excite the respiratory center when it is oppressed and weakened breathing, spasmodic state of the musculature of the gastrointestinal tract, with maternal paresis in cows, overfatigue, various diseases of infectious and toxic origin.

9. Contraindications to the use of the drug is not established.

10. Sodium caffeine-sodium benzoate A 20% solution for injection is administered subcutaneously in the following doses (in ml per animal):


 Type of animals

Dose of the drug, ml

horses and cattle

5,0 — 10,0

small animals and pigs

0,5 — 2,0


0,2 — 0,5

Doses and timing of application depend on the weight of the animal and the course of the disease.

11. When an overdose is observed tachycardia, arrhythmia, vomiting.

12. Features of the drug at the beginning of application or when it was abolished is not revealed.

13. Failure to comply with the recommended interval with repeated administration may lead to a decrease in the effectiveness of the drug.

14. At recommended doses, 20% caffeine-sodium benzoate does not cause side effects and complications in animals.

15. The drug is compatible with other medicines.

16. Livestock products during and after use are used without restrictions.

IV. Personal prevention measures

17. When working with Caffeine-sodium benzoate 20%, you should follow the general rules of personal hygiene and safety, provided when working with medications.

18. Do not drink, smoke or eat while working with a medicine. After work, you should wash your hands with warm water and soap.

19. In case of accidental ingestion of 20% caffeine-benzoate sodium on the skin or mucous membranes, immediately wash it off with running water and soap. In the event of an allergic reaction, you should immediately contact a medical institution (with you to have instructions for the use of the drug or a label)

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