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on application of medicine ” Tablets

oxytetracycline hydrochloride” for the treatment of bacterial

infections in animals.

(Organization-developer: LLC Firm “Biochempharm”, 600910, Vladimir region, rainbow, quarter 16, box 74)

I. General information

1. Trade name: oxytetracycline hydrochloride Tablets.

International non-proprietary name: oxytetracycline hydrochloride.

2. Dosage form: tablets. Each tablet contains 0.25 g of the active substance.

3. In appearance, the drug is a tablet of greenish-yellow color, round shape with a flat surface.

Shelf life of the drug under storage conditions in a closed package-2 years from the date of production. Do not use the medicine after its expiration date.

4. Produce oxytetracycline hydrochloride Tablets packaged in 50, 100, 250, 500, 1000 pieces in polymer banks for medicines.

Each package is marked with an indication of the manufacturer, its address and trademark, the name of the drug, the name and content of active substances, series number, date of manufacture, shelf life, storage conditions, bar code, state registration number, the number of tablets in the Bank, the inscription “for veterinary use”, designation TU, and provide instructions for use.

5. Store oxytetracycline hydrochloride Tablets in a dry, protected from direct sunlight at a temperature of 5°C to 25°C.

6. Oxytetracycline hydrochloride tablets should be stored out of the reach of children.

7. Unused product with expired shelf life is disposed of in accordance with applicable law.

8. Is dispensed without prescription veterinary doctor.

II. Pharmacological properties

9. Pharmacotherapeutic group: antibiotic of the tetracycline group.

10. Oxytetracycline is a bacteriostatic antibiotic whose mechanism of action is to disrupt protein synthesis in interaction with ribosomes, as well as to reduce the permeability of the cytoplasmic membrane of sensitive microorganisms. The drug has a wide spectrum of action on gram-positive and gram-negative microorganisms: Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Nocardia spp., Brucella spp., Haemophilus spp., Bordetella spp., Bartonella spp., Shigella spp., Yersinia spp., Actinomyces spp., Bacillus anthracis, E. coli, Pasteurella spp., Salmonella spp., as well as protozoa (Protozoa), Mycoplasma (Mycoplasma spp.), Rickettsia (Rickettsia spp.) and chlamydia (Chlamydia).

     After the use of tablets in the therapeutic dose, the maximum concentration of the active substance is created in the blood in the first 2-3 hours and is kept at the therapeutic level of 8-12 hours. The antibiotic is excreted from the body mainly in the urine.

III. The order of application

11. Oxytetracycline hydrochloride tablets are used for agricultural and small Pets, as well as for poultry in colibacteriosis, pasteurellosis, salmonellosis, mycoplasmosis, staphylococcal infection, rickettsiosis, actinomycosis and other diseases caused by microorganisms sensitive to tetracycline group drugs.

12. Contraindications to the use of oxytetracycline tablets is an increased individual sensitivity of animals to tetracycline antibiotics. Do not use for the treatment of lactating animals and animals with dystrophic liver lesions. Do not administer the drug to laying hens during oviposition.

13. The drug is given individually or by a group method with food or water for the active ingredient in a dose of g / kg: young cattle and small cattle, camels, dogs and cats 0.01-0.02; pigs 0.015-0.03; chickens, turkeys and ducks 0.02-0.05 twice a day for 3-7 days. Poultry drug can be used with water at the rate of 10 tablets in 5 liters of water and drink twice a day for 5-7 days. When using the drug group method tablets should be thoroughly crushed and mixed with food.

14. Symptoms of overdose in the appointment of the drug according to the instructions is not established.

15. Features of the Tablets oxytetracycline hydrochloride at the beginning of use or when it is canceled is not revealed.

16. Failure to follow the recommended interval for repeated administration of the drug may lead to a decrease in its effectiveness. If you miss the next dose of the drug, its use is resumed as soon as possible in the same dosage and according to the same scheme.

17. With prolonged use of the drug, dysbiosis is possible. In the event of allergic reactions to cancel the drug, prescribe antihistamines and calcium supplements.

18. The use of the drug does not exclude the use of other drugs specific, pathogenetic and symptomatic therapy. Do not use the drug with antibiotics of penicillin, polymyxin and drugs containing calcium, aluminum and magnesium compounds, as well as with milk and dairy products.

19. Slaughter of animals for meat is allowed not earlier than 7 days after the last use of the drug. Meat of animals forcibly killed before the expiry of the specified period can be used for feeding carnivores or for processing into meat and bone meal.

IV. Personal prevention measures

21. When working with the drug, the General rules of personal hygiene and safety, provided for when working with drugs, should be observed.

22. When working with oxytetracycline hydrochloride Tablets, it is forbidden to drink, smoke and eat. Avoid contact with the skin and mucous membranes. After working with the drug, wash your hands with soap and water. Empty container from under the drug should not be used for household purposes; it should be disposed of with household waste.

23. In case of accidental contact of the drug with the skin or mucous membranes, immediately wash them with plenty of running water. In case of allergic reactions or accidental ingress of the drug into the human body, you should immediately contact a medical institution (you should have the instructions for use of the drug and the label).

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