INSTRUCTIONS
of using Iodomast for the treatment of mastitis in cows
(Organization-developer: “BioKhimPharm”, Vladimir region, Raduzhny town)
I. General information
1. Trade name of the medicinal product: Iodomast.
International non-proprietary name: iodine, bismuth, prednisolone, procaine.
2. Dosage form: topical solution. Iodomast contains iodine, bismuth salt, prednisolone, procaine and prolonging base.
3. Iodomast is produced in the form of 10, 100, 200, 400 and 1000 ml glass or polymer bottles and 10 ml plastic injection syringes for intracisternal administration.
4. Store the drug in the dark place at a temperature of 50C to 250 C. The shelf life of the drug – 1 year from the date of release, indicated on the label. Do not use the medicinal product after the expiration date.
5. The drug is stored in places inaccessible to children.
6. Iodomast is disposed of in accordance with applicable law.
II. Pharmacological properties
7. Pharmacotherapeutic group of the drug: combined antibacterial drugs.
Iodine in the composition of Jodomast causes a pronounced bactericidal and bacteriostatic effect against a wide range of microorganisms – pathogens of mastitis, has a general stimulating effect on the immune system of the udder and uterus.
Bismuth in the composition of the drug has a powerful analgesic, anti-edematous and astringent action in the pathological focus.
Procaine (novocaine) has a local analgesic effect, reduces the reaction of tissues to the irritating effect of other components of the drug.
The hydrophilic basis of Jodomast is physiologically indifferent: as part of the preparation, it eliminates the irritating effect of the active components on the mucous membranes of the glandular epithelium of the mammary gland; adsorbs and neutralizes microbial and tissue toxins.
Consistency of Jodomast promotes uniform distribution of the drug in the pathological focus, mixing with exudate and maximum contact of active components with the mucosa in the lesion. The preparation is mixed in any proportions with water, forming a stable suspension.
III. The order of application
8. With a therapeutic and prophylactic goal for hidden pathologies of the udder of cows during lactation:
– irritation of the breast;
– Aseptic small focal inflammation of the breast;
– Subclinical mastitis.
For the treatment of cows suffering from clinical mastitis:
– catarrhal inflammation;
– catarrhal-purulent inflammation;
– purulent-catarrhal inflammation;
– with an alternative lesion of breast tissue (an admixture of blood in milk).
9. In the appointment of Jodomast in the recommended doses of contraindications for use is not established.
10. The drug is injected heated to a temperature of 370C-390C in the problematic parts of the udder intracisternally through the teat canal. Before applying the preparation, the contents of the patient quarter of the udder are dispensed into a separate bowl and disposed of, and the nipple is disinfected with 70% ethyl alcohol.
When using a syringe tube, the cannula is tightly pressed against the opening of the teat canal, fixed firmly by the fingers and gently press the piston into the breast cistern. The drug, packaged in vials, is injected via a syringe through a milk catheter in a manner similar to that described.
With clinical mastitis, Iodomast is injected into the mammary gland at a dose of 10.0 ml after each milking until the signs of inflammation are eliminated (3-5 installations).
With latent pathology (irritation, aseptic inflammation, subclinical mastitis) in the udomast udder, injected into the mammary gland three times after each milking at a dose of 5.0 ml (with triple milking) or twice in a dose of 10.0 ml (with a double milking).
11. When you inject Jodomast into the body, an overdose is impossible, since it does not accumulate in organs and tissues.
12. Features of the action when the application of Jodomast or when it was abolished is not revealed.
13. In case of missing the next treatment, it is recommended to hold it as soon as possible. Further, the processing interval does not change.
14. Some animals (3-5% of the treated number) after intracisternal administration, have udder connective tissue in the form of cold edema, a manifestation of hypersensitivity to iodine preparations. However, the introduction of Iodomast does not stop. After the course of treatment, udder condensation disappears within 10-12 hours.
When the drug is injected into an insufficiently quartered udder, clotting of casein with signs of tissue edema can be noted (the curdling of milk residues due to the acid reaction of the drug). In this case, it is necessary to immediately take measures to carefully sdeyivaniyu within a few races (manual milking) until the termination of the allocation of clots. Medical treatment is not taken.
15. The use of Iodomast does not exclude the use of other drugs with specific, pathogenetic and symptomatic therapy.
16. In the treatment of cows with subclinical lesions of the breast, milk is used without restrictions. When treating cows with clinical mastitis, milk is disposed of only from the affected parts until the signs of inflammation disappear (flakes of casein, pus, blood); in the future, milk is used without restriction, even with the continuation of treatment.
Meat of slaughter animals using the drug is used without restrictions.
IV. Personal prevention measures
17. When working with the drug, Iodomast should observe the general rules of personal hygiene and safety, provided when working with medicines for animals.
18. Do not drink, smoke or eat while working with a medicine. After working with Jodomast, wash your hands with soap and water.
19. It is prohibited to use empty containers for medicinal products for household purposes.