INSTRUCTION
of using CYPEROL for the control of blood-sucking insects and ectoparasites of animals (organization-developer: “BioKhimPharm”, Raduzhny, Vladimir region).
I. General information
1. Trade name of the preparation: Tseperol. International non-proprietary name: permethrin (Permethrin), cypermethrin (Cypermethrin).
2. Dosage form: solution for external use. The drug as active ingredients contains synthetic pyrethroids permethrin (Permethrin) and cypermethrin (Cypermethrin), as well as solvents. In appearance, the preparation is an oily colorless or pale yellow transparent liquid with a specific odor.
The preparation is ready to be ready for use, packed in spray bottles of 30 and 100 ml each, aerosol cans of 170 g, bottles of a dropper 10 ml, non-propellant cylinders with a sprayer of 500 and 1000 ml or polyethylene cans of 0.5; 1.0; 2.5; 5,0 and 10,0 l. The shelf life of the drug, if stored in a sealed container, is 18 months from the date of manufacture. Do not use the drug after the expiration date.
3. Each package is marked with the manufacturer’s organization, its address and trademark, the name, purpose and method of application, the name and content of the active substances, the volume and / or weight of the preparation in the package, the inscriptions “For Veterinary Medicine”, the serial numbers, date of manufacture, expiry date, storage conditions, “Shake before use”, designations of technical specifications and provide instructions for use.
The shelf life of the drug, if stored in a sealed container, is 18 months from the date of manufacture. Do not use the drug after the expiration date.
4. Store the preparation in the manufacturer’s closed container in a fire-safe room away from heating appliances and direct sunlight, separate from fodder and food products at temperatures from minus 20 ° C to 40 ° C.
5. Keep rhe drug out of the reach of children.
6. Dispose of unused product with expired shelf life in accordance with legal requirements.
II. Pharmacological properties
7. Pharmacotherapeutic group of medicinal product: a means for fighting ectoparasites. Pharmacological properties of the preparation of cyperol are due to the active ingredients that make up its composition – synthetic pyrethroids permetrin and cypermethrin. Synthetic pyrethroids are insecticidal-acaricidal agents of intestinal-contact action.
Are active against different species of ticks, flies, lice and other ectoparasites of animals. Violate the function of the nervous system, acting on sodium-potassium channels and calcium exchange in the synapses, which leads to the release of excessive amounts of acetylcholine during the passage of a nerve impulse.
Poisoning in arthropods is manifested in a strong excitation, lesion of motor centers, accompanied by paralysis and subsequent death. The drug has a long lasting effect on the skin-hair covering of animals and treated surfaces of premises.
The drug Cyperol for toxicity refers to moderately toxic (hazard class III according to GOST 12.1.007-76). In the recommended mode of administration and doses, it does not have a skin-resorptive, local-irritant and sensitizing effect.
III. The procedure of application
8. The drug is used to control flies, sucking insects, ectoparasites, causing scabies of cattle, pigs, sheep, rabbit psoroptosis, demodecosis and ode-deformosis of dogs, cats, fur animals.
9. Before processing, the aerosol can is shaken, the protective cap is removed and, by pressing the spray head, the aerosol torch is directed from a distance of 25-30 cm to the skin-hair cover of the animal. The release rate of the drug is 2.4 g / s.
From one aerosol can, 170 grams are processed with 2-3 heads of cattle, 10-12 head of sheep, 12-15 pigs or 10-12 dogs. The treatment is carried out depending on the weight of the animal for 15-20 seconds. When using the drug in a non-propellant container, its body is pressed with a hand until a jet of the drug emerges from the nozzle and, by pressing the handle of the nebulizer, is processed.
From the spray bottle, remove the protective cap and, by pressing the spray head, perform the treatment. The drug is sprayed from a distance of 25-30 cm. The rate of drug release is 2.0 g / s. From one non-propellant balloon 500 ml (1000 ml) – 7-8 (15-16) heads of cattle or 12-15 (25-30) pigs.
Prepacked in plastic jerricans, the drug is sprayed with various types of manual, mounted, trailed, self-propelled sprayers and devices for aerosol disinfection (TAN, RCC, SAG-1, etc.). For the treatment of one animal, the drug consumption is 35 to 60 g. The drug, packaged in droppers, is used to treat local skin lesions with a cotton swab, or buried in the auricle when treating dog demodecosis, rabbit psoroptosis, dog otodectosis and fur animals. Before working with the dropper, remove the protective cap.
10. Treatment against Dipterous insects (flies, flies, mosquitoes, gnats, midges) is carried out once during their mass summer and repeated as necessary. Aerosol of the drug is applied to the entire surface of the body, especially the head, abdomen and extremities area based on the above stated consumption rates.
The treatment of animals is carried out outdoors individually or in groups. Similarly, the drug is used for sifunkulatozah cattle and pigs. To combat entomosis of mink and dogs, the preparation is sprayed onto the entire surface of the animal’s body for 2-3 and 5-7 seconds, respectively.
Pregnant mink is treated no later than two weeks before the pupping. Treatment of mink with puppies is carried out at an ambient temperature of at least 10-15 0С. Sheep, suffering from psoroptosis, treat only the cut, irrigating the entire body of the animal. With a preventive purpose, the treatment is carried out once.
With a pronounced disease, treatment is carried out twice with an interval of 8-10 days. The drug consumption is 14-16 g per animal (1 aerosol can for 10-12 animals, 1 non-propellant balloon for 30-32 animals). When scabies and demodecoses of cattle and pigs, the drug in the form of an aerosol is applied to the skin-hair covering of the entire surface of the body, regardless of the degree of damage.
The treatment is carried out twice with an interval of 8-12 days. At demodecosis of dogs, the affected areas of the body before treatment are cleaned of crusts and scabs with a cotton-gauze swab. Then, to the affected areas and adjacent areas of healthy skin from the periphery to the center, apply tsiperol in the form of an aerosol for 1 second, or, moistened with a swab at a rate of 0.1-0.3 ml per 1 kg of animal weight. To avoid licking Cyperol, the jaws of the animal are closed with a loop of braid, which is removed after 15 minutes after applying the preparation.
Animals with extensive skin lesions are treated in two doses at intervals of 1 day, applying the drug first to one, and then to the other half of the affected surface. The treatment is carried out four times at intervals of 5-7 days.
In case of psoroptosis of rabbits, otodectosis of fur animals and dogs, the ear form of sarcoptic swine, the ear canal is previously cleaned from scabs and crusts moistened with hydrogen peroxide. Ciperol in aerosol packaging is applied from a distance of 25-30 cm for 2 seconds (when using the drug in non-propellant balloons, press the spray gun 2 times), directing the torch on the inner surface of the auricle.
For more complete treatment, the auricle is folded in half and slightly massaged by its base. The treatment is carried out twice with an interval of 3-5 days. Repeat the treatment as necessary.
11. Symptoms of overdose when using the drug in accordance with this instruction is not established.
12. Features of the action of the drug at the beginning of the application of tsiperol or when it is canceled is not revealed.
13. Passage of the next dose of the drug (treatment) should be avoided, as this may lead to a decrease in therapeutic effectiveness. In the case of missing one or more doses, the drug is resumed as soon as possible in the same dosage and according to the same schedule.
14. Adverse events and complications in the use of tsiperol in accordance with this instruction is not established.
15. The use of ciderol does not exclude the use of other drugs.
16. Slaughtering of animals for meat is allowed not earlier than 10 days after the last treatment with tsiperolom. When forced to slaughter a predetermined period, meat is used for animal feed, or for the production of meat and bone meal.
IV. Personal prevention measures
17. Work with aerosols of the preparation Ciperol is carried out in clothing and personal protective equipment (robe, goggles, rubber boots, gloves) veterinary specialists or instructed persons. To prevent inhalation of the drug, it is necessary to use a gauze dressing with a cotton pad, respirator or gas mask.
18. Do not smoke, eat or drink while working. After work, the overalls are removed and hung out for airing. The face and hands are thoroughly washed with warm water and soap. Store packages with the drug Ciperol in a non-residential area under lock and key, away from direct sunlight, heating devices and open fire.
On the container there should be a label indicating the name of the preparation, its formulation and the content of the active substance. For each batch of the drug must be a factory passport. It is not allowed to store and transport aerosol cans together with food and fodder.
19. If the product gets into the eyes, they should be washed abundantly with a stream of clean water or with a 2% solution of baking soda for 5-10 minutes. When irritating the mucous membrane of the eye – drip with a solution of albucid, with soreness – 2% solution of novocaine. If the throat irritates, rinse it with a 2% solution of drinking soda, make soda inhalation.
If the product is accidentally applied to the skin, it should be thoroughly washed off with soap and water. If signs of poisoning appear, you should immediately seek medical help.
