INSTRUCTION
on the use of Cefamast as an antibacterial drug for the treatment of mastitis in cows, mares, camels, sheep and goats
(organization-developer: LLC Firm “Biochempharm”, Vladimir region, Raduzhny)
I. General information
1. Trade name of the medicinal product: Ceramist (Cefamaste).
International nonproprietary name: Cefotaxime sodium, prednisolone.
2. Dosage form: suspension for intracisternal application.
In appearance, Cefamast is a thick viscous suspension from white to light yellow in different shades, at 35 ° C-40 ° C it acquires fluidity and transparency. The drug as active ingredients in 1 ml contains Cefotaxime sodium-50 mg, prednisolone-1 mg and excipients: stearic acid, aluminum stearate and vaseline oil to 1 ml.
3. Cefamast is produced packaged in hermetically sealed plastic syringes-tubes for intracysternal administration with a capacity of 10 ml.
Do not use Cefamast after the expiration date.
4. Store the drug in the closed packaging of the manufacturer, in a dry, protected from light place, at a temperature of minus 25 ° C to 25 ° C.
Shelf life under storage conditions – 3 years from the date of production.
5. Ceramist should be stored in places inaccessible to children.
6. The drug is disposed of in accordance with applicable law.
II. Pharmacological properties
7. Pharmacotherapeutic group of the drug: combined antibacterial drugs.
Cefotaxime sodium, a part of Caramanta, has a wide spectrum of antimicrobial (bactericidal) action. It is active against gram-positive microorganisms (Staphylococcus spp., forming and non-forming penicillinase, most strains of Streptococcus spp., including pneumococci, Corynebacterium diphtheriae), gram-negative microorganisms (Escherichia coli, Salmonella spp., Shigella spp., Proteus mirabilis, Klebsiella spp., Haemophilus influenzae, Enterobacter aerogenes, Neisseria gonorrhoeae). Antibiotic resistant indole-positive strains of Proteus (P morgani. P. vulgaris, P. rettgeri), does not act on Rickettsia, viruses, fungi, protozoa. Like penicillins, inhibits the synthesis of the cell wall of bacteria.
Prednisolone has anti-inflammatory and mild analgesic effect.
The consistency of the dosage form of the drug contributes to its uniform distribution over the mucous membrane of the affected organ, the transport of active components to the pathological focus and the maximum contact of active components with the lesion.
Cefamast on the degree of impact on the body belongs to the 3rd class of danger – moderately dangerous substances (according to GOST 12.1.007-76).
III. The order of application
8. Cefamast is prescribed intracysternally in the treatment of cows, mares, camels, sheep and goats, patients with subclinical and clinical forms of mastitis, both in lactation and in dry periods.
9. Contraindicated in animals with increased individual sensitivity to the components of the drug.
10. The drug is heated to 35 ° C, thoroughly shaken. Remove the cap and completely inject the contents of the syringe (10 ml) into the milk canal of the affected udder lobe. Squeezing the tip of the nipple, carefully remove the syringe and conduct a light massage of the patient’s udder lobe. Lactating animals cefamast is administered intracysternally at intervals of 12 hours before recovery, with a subclinical course 1 time per day for 3 days. In the dry period, the drug is administered 3 times at intervals of 3-4 days.
11. Symptoms of overdose when using the drug in accordance with this instruction is not established.
12. In case manifestations of have animal signs of individual heightened sensitivity to drug in the early treatment, his the use of should abolish and to appoint means symptomatic therapy.
13. Failure to comply with the recommended interval for repeated administration of Cefamast can lead to a decrease in the effectiveness of its use. At the admission of the next dose its application resume as soon as possible.
14. Side effects and complications with proper use and dosage of the drug is not observed. In animals that are sensitive to Atamasco, allergic reactions are possible.
15. The use of Cefamast does not exclude the use of other drugs specific, pathogenetic and symptomatic therapy.
16. Slaughter of animals for meat is allowed 7 days after the last administration of the drug. Meat of animals forcibly killed before the expiration of this period can be used for feeding fur-bearing animals.
The use of milk for food purposes is allowed no earlier than 3 days after the last administration of Cefamast. Milk from healthy udder lobes, obtained before the deadline, can be used after boiling in animal feed. Milk from patients shares-only after full clinical recovery, confirmed mastitis tests, but not before the specified term.
IV. Personal prevention measures
17. When working with Cefamast, the General rules of personal hygiene and safety, provided for when working with medicines, should be observed.
18. When working with the drug, it is forbidden to drink, smoke and eat. After working with Seamaster should wash hands with soap and water.
19. In case of contact with the skin and mucous membranes should be washed with plenty of running water. People with hypersensitivity to Seamast should avoid direct contact with the medicinal product. In case of allergic reactions and / or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have the instructions for use of the drug or the label).
